1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Here are the key drug-food Interactions:
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
Show Moreuspaid@delphong.comacleschema-onlineaccutanexplosionurepharmacygenericcompanichttps://www.delphong.com/en/comp/accutane/comp/compa...AddToPharmacyListPrecautionsDisclaimer: Content on this page is for information purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a physician or pharmacist for any health advice or concerns.Cialis UsageDo not take Cialis more than once a day.
Consult Your DoctorIf you are experiencing a sudden decrease or loss of vision, contact your doctor right away.
Possible Side EffectsThese may be signs of a severe adverse reaction to this medication. If you experience any such side effects, seek medical attention immediately.
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
Show More Nov 1, 1, 3, 5Share:Use of Cialis for menopausal symptoms is not recommended, as it can cause potential depression and mood swings. As with all prescription medications, inform your doctor of any medical conditions you used to get pregnant, started treatment with a taking, or whether you have used any other medications.
Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Share Browseina, a pharmacy service offered by the maker of menopausal pregnancy service.NoShow More Nov 1, 5, 10, 14, or 15As with all prescription medication, be sure to provide accurate information about your past, current, or any sexual problems. This can include whether the symptoms are affecting your health-related well-being.
Abstract
Treatment of hypertension (high blood pressure) with oral tadalafil (Cialis) is well-accepted. The aim of the present study was to investigate the clinical response and safety of tadalafil compared with diclofenac (Vardenafil) in patients with moderate to severe hypertension. Patients were randomly allocated to two treatment groups (tadalafil + diclofenac) and placebo groups (n = 36). The primary outcome measure was the change in blood pressure (BP) from baseline to treatment.
Methods
Eligible patients were treated with either tadalafil (n = 30), diclofenac (n = 30), or placebo. In the tadalafil group, the mean change in BP from baseline was 1.0 mmHg to 4.4 mmHg (n = 30), while in the diclofenac group, the change in BP was 0.8 mmHg to 8.9 mmHg (n = 30). The primary objective of this study was to compare the efficacy of two different treatment groups in patients with hypertension. The secondary objectives were to compare the safety profile of the two groups with respect to safety in patients with moderate to severe hypertension.
Results
The primary outcome measure was change from baseline in BP from baseline to treatment in both the tadalafil + diclofenac group and the placebo group. There was no significant difference in baseline changes from baseline in either the tadalafil + diclofenac group or the placebo group. The mean change from baseline in mean BP from baseline to treatment was -0.4 mmHg, and the change from baseline to treatment was 0.8 mmHg in the tadalafil + diclofenac group. There were no significant differences in change from baseline in mean BP from baseline to treatment between the tadalafil + diclofenac group and the placebo group.
Conclusion
The tadalafil group showed a statistically significant higher mean BP reduction compared with the placebo group (P< 0.01). This was more evident in patients with moderate to severe hypertension (n = 30).
Citation:Athletes P, Lee J, et al. (2022) Effect of tadalafil and diclofenac on the response to treatment with tadalafil (Cialis). Pharmacoeconomics and Health Sciences Research
,BMJ1996;380:842–843. doi: 10.1046/j.1365-6109.20090.00160
Last updated: July 2025.
Effect of tadalafil and diclofenac treatment on blood pressure in patients with moderate to severe hypertension.JAMA1996;315:2180-2198. doi: 10.1001/jama-aji.1996.315.2180Copyright © 2020. This is a public sale, copyright, and belongs to a trademark disclosure company ®. All rights reserved.
Published online July 2025. doi: 10.1TB. Accessed July 2025.1998;311:2638-2643. doi: 10.1001/jama-aji.1998.31.2238© 2020-2025 Bangkok Pharmacist Association.
1998;315:2638-2643. doi: 10.1001/jama-aji.